Osteogenesis Imperfecta: Report of Two Consecutive Cases in a Monogamous Family from South-West, Nigeria

Abstract

Osteogenesis imperfecta is a heritable disorder of connective tissue, affecting both bone and soft tissue. It is characterized by multiple fractures, bone deformities, short stature, ligament laxity, bluish sclera, among others. We present a monogamous family with two affected consecutive siblings, aged 5 and 3 years respectively, and a third sibling, three days old, who is unaffected.