Nigerian Journal of Parasitology

The AJOL site is currently undergoing a major upgrade, and there will temporarily be some restrictions to the available functionality.
-- Users will not be able to register or log in during this period.
-- Full text (PDF) downloads of Open Access journal articles will be available as always.
-- Full text (PDF) downloads of subscription based journal articles will NOT be available
We apologise for any inconvenience caused. Please check back soon, as we will revert to usual policy as soon as possible.

DOWNLOAD FULL TEXT Open Access  DOWNLOAD FULL TEXT Subscription or Fee Access

Diversities of Anopheles gambiae ss and Plasmodium falciparum in Minna, Nigeria

I.C.J. Omalu, S.S. Eke, I.K. Olayemi, E.C. Egwim, H.U. Yamman, I.M. Ocha, M.T. Ogunniyi, O.S. Ajibaye, C.A. Otuu, C.I. Nnaji, P.U. Inyama


Genetic diversities of Anopheles gambiae ss and Plasmodium falciparum is a major challenge in malaria control as it affects the vector, treatment and production of a vaccine. The aim of the study is to identify the genetic variabilities of A. gambiae ss using the A. gambiae species-specific multiplex Polymerase Chain Reaction (PCR) and P. falciparum using merozoite surface protein (msp2) as antigenic marker. Results revealed that the A. gambiaes ss identified were of the M-forms and the two families of msp-2, FC27 and 3D7 were observed among the isolates of P. falciparum. Eleven (11) number of genotypes were recorded with FC27 having the highest frequency of 8(26.67%) while 3D7 had the least number of genotypes encountered with 3(10%). The allelic frequency of FC27 type was higher 29(96.67%) than 3D7 alleles with 26 (86.67%). There is no significant difference found in the distribution of FC27 alleles and 3D7 alleles in the study populations (p>0.05). The observed population genetics of A. gambiae ss and P. falciparum is likely to be a consequence of the high transmission intensity. This has important implications for malaria control strategies and vaccine production.

Keywords: Genetic veriabilities; malaria control strategy.

Full Text:

No subscription journal articles available during site upgrade.

AJOL African Journals Online