Foetal alcohol syndrome: an osteometric evaluation in the wistar rat animal model

  • SS Adebisi Department of Human Anatomy, Faculty of Medicine, Ahmadu Bello University, Zaria, Nigeria
Keywords: Foetal alcohol syndrome, bone anomaly, osteometry, wistar rat

Abstract

Background: Foetal alcohol syndrome had been reported as a common feature in the off – springs of alcoholic mothers; and craniofacial and limb bones anomalies are usually some of the cardinal features of foetal alcohol syndrome (FAS).

Methods: These features were osteometrically assessed in the cranial and limb bones of the harvested foetuses of pregnant Wistar rats' models.

Results: Mal-developments and stunted growth with no evidence of post treatment reparation or recovery were observed in the ethanol – treated rats.

Conclusion: This observation is possibly indicative of another dimension at improving our understanding of the mechanism of the toxicity of ethanol.

Key Words: Foetal alcohol syndrome, bone anomaly, osteometry, wistar rat

Nigerian Journal of Surgical Research Vol.5(1&2) 2003: 160-165
Published
2004-06-04
Section
Articles

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eISSN: 1595-1103