Effect Of The Extracts Of Musanga Cecropioidis Budsheath On The Contractility Of The Rat Uterus

Abstract

The effect of the water, ethanol and chloroform extracts of the stipular Budsheath of Musanga cecropiodis (cecropiaceae) on the contractility of the isolated uterine rings was investigated. Water extract of Musanga cecropioidis did not show any effect on the contractility of the uterus. However, the ethanol solution of the ethanolic extract significantly reduced and even completely abolished the contractile responses induced by either oxytocin, acetylcholine or serotonin. The ethanol solution of the chloroform extract also caused inhibition of the contraction induced by oxytocin but the effect was not as marked as that of the ethanol solution of the ethanolic extract.

Nigerian Quarterly Journal of Hospital Medicine Vol.9, No.3 (1999) pp. 241-243