Nigerian Quarterly Journal of Hospital Medicine

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Membrane Stabilizing Activity And Phytochemistry Of Hibiscus rosa-sinensis Leaves

A A Osuntoki, T A Oyede, A A Otunba


The human erythrocyte membrane stabilizing activity of saline extract of Hibiscus rosa-sinensis leaves was investigated as part of efforts at validating its use as anti-arthritic and anti-inflammatory agent. The results of the membrane stabilizing activity of the extract, when compared to two non-steroidal anti-inflammatory drugs (Acetylsalicylic acid and indomethacin) used as positive controls, showed that the extract has very potent membrane stabilizing properties which may justify the use of H. rosa-sinensis leaves in anti-inflammatory ethnomedical preparations. Phytochemical examination of the leaves showed the presence of alkaloids, tannins, flavonoids, steroids, saponins, triterpenic steroidal glycosides and leucoanthocyanydines.

NQJHM Vol. 16 (2) 2006: pp. 53-55
AJOL African Journals Online