Validation of four human point-of-care glucometers for blood glucose determination in rabbits.

Abstract

This study compared the accuracy and agreement of four commonly available point-of-care glucometers (PCGs) with a reference method for blood glucose determination in rabbits. Forty (40) healthy rabbits were used for the study. Blood (2 ml) was collected from the ear vein and the four PCGs were used to determine the blood glucose concentrations immediately. Thereafter, the samples were placed into test tubes without anticoagulant. The samples were processed appropriately and the serum harvested. Blood glucose test kit was used to measure glucose concentrations in serum by the glucose oxidase method. Data generated were analysed using Correlation coefficient, Student’s t-test and Bland Altman Plot. Results showed that the mean values generated by the PCGs were in agreement with the values generated by the laboratory method. Therefore, the four PCGs can be used to determine blood glucose concentration in rabbit with reasonable accuracy.