Oral verrucous carcinoma complicating a repetitive injury by the dental prosthesis: a case report

  • L Rahali
  • Y Omor
  • K Mouden
  • Y Mahdi
  • H Elkacemi
  • S Elmajjaoui
  • R Latib
  • T Kebdani
  • MN Boujida
  • N Benjaafar


Verrucous carcinoma (VC) is an unusual, well differentiated, and low-grade type of squamous cell carcinoma, characterized by benign histology and cytology but markedly invasive clinical behavior. They have a predilection for squamous mucosae, particularly those of the head and neck region. Many factors have been associated with its pathogenesis, including the presence of previous skin lesions; VC arising from a prosthesis injury is rare. Here we reported a case of VC of oral cavity a particularly very aggressive, arising from prosthesis injury. Regardless of the treatment modality, given new insights into the possible aggressivity of this tumor, radiotherapy associated to chemotherapy may be a more appropriate primary treatment compared with the significant local morbidity associated with surgery.

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eISSN: 1937-8688