Adenocarcinoma arising from chronic perianal crohn’s disease: a case report

  • Hanane Massit
  • Meryem Edderai
  • Rachida Saouab
  • Hassan Seddik
  • Jamal El Fenni
  • Ahmed Benkirane
Keywords: Crohn´s disease, perianal disease, perineal adenocarcinoma


Malignant transformation of perineal fistula in Crohn's disease has rarely been reported. We report a case of Crohn's disease with recurrent perineal fistulas. A 36-year-old male, diagnosed with Crohn's disease at the  age of 24, developed adenocarcinoma in an anorectal fistula that had existed for years. He was treated with adjuvant chemoradiotherapy but died. A high index of suspicion and regular surveillance is recommended in chronic anorectal fistulas in Crohn's disease. The shorter duration of Crohn's fistulas prior to malignant  degeneration necessitates an aggressive approach to rule out cancer.

Key words: Crohn´s disease, perianal disease, perineal adenocarcinoma


Journal Identifiers

eISSN: 1937-8688