Polymyositis anti-SRP antibodies and pregnancy about 2 cases

Cissé Ousmane; Ba El Hadji Makhtar; Ba Fatoumata; Gams Daniel Massi; Daddah Sami Mouhamed Lémine; Diop-Sène Marieme Soda; Sow Adjaratou Dieynaba; Basse Anna; Seck Lala Bouna; Ndiaye Moustapha; Diop Amadou Gallo; Ndiaye Mouhamadou Mansour

PROMOTING ACCESS TO AFRICAN RESEARCH

Pan African Medical Journal

Polymyositis anti-SRP antibodies and pregnancy about 2 cases

Cissé Ousmane, Ba El Hadji Makhtar, Ba Fatoumata, Gams Daniel Massi, Daddah Sami Mouhamed Lémine, Diop-Sène Marieme Soda, Sow Adjaratou Dieynaba, Basse Anna, Seck Lala Bouna, Ndiaye Moustapha, Diop Amadou Gallo, Ndiaye Mouhamadou Mansour

Abstract

Anti-SRP myopathy represents 4 to 6% of all the inflammatory myopathies. It has been described since the 80s and its influence on pregnancy and vice versa has been highlighted recently. We report two cases of anti-SRP myopathy associated with pregnancy. In the first case, the initial manifestations of the disease started in post partum and the second case was an anti-SRP myopathy patient before pregnancy. In both cases we objectified outbreaks during post-partum. Pregnancy seems to promote outbreaks. The inactive myopathy seems to presents no serious maternal-fetal complications as well as the usual dose of corticosteroids. The treatment (corticosteroid) during pregnancy is indicated given the risk of worsening during the post-partum.

The Pan African Medical Journal 2016;24