Polymyositis anti-SRP antibodies and pregnancy about 2 cases

Cissé Ousmane; Ba El Hadji Makhtar; Ba Fatoumata; Gams Daniel Massi; Daddah Sami Mouhamed Lémine; Diop-Sène Marieme Soda; Sow Adjaratou Dieynaba; Basse Anna; Seck Lala Bouna; Ndiaye Moustapha; Diop Amadou Gallo; Ndiaye Mouhamadou Mansour

PROMOTING ACCESS TO AFRICAN RESEARCH

Pan African Medical Journal

The AJOL site is currently undergoing a major upgrade, and there will temporarily be some restrictions to the available functionality.
-- Users will not be able to register or log in during this period.
-- Full text (PDF) downloads of Open Access journal articles will be available as always.
-- Full text (PDF) downloads of subscription based journal articles will NOT be available
We apologise for any inconvenience caused. Please check back soon, as we will revert to usual policy as soon as possible.

Polymyositis anti-SRP antibodies and pregnancy about 2 cases

Cissé Ousmane, Ba El Hadji Makhtar, Ba Fatoumata, Gams Daniel Massi, Daddah Sami Mouhamed Lémine, Diop-Sène Marieme Soda, Sow Adjaratou Dieynaba, Basse Anna, Seck Lala Bouna, Ndiaye Moustapha, Diop Amadou Gallo, Ndiaye Mouhamadou Mansour

Abstract

Anti-SRP myopathy represents 4 to 6% of all the inflammatory myopathies. It has been described since the 80s and its influence on pregnancy and vice versa has been highlighted recently. We report two cases of anti-SRP myopathy associated with pregnancy. In the first case, the initial manifestations of the disease started in post partum and the second case was an anti-SRP myopathy patient before pregnancy. In both cases we objectified outbreaks during post-partum. Pregnancy seems to promote outbreaks. The inactive myopathy seems to presents no serious maternal-fetal complications as well as the usual dose of corticosteroids. The treatment (corticosteroid) during pregnancy is indicated given the risk of worsening during the post-partum.

The Pan African Medical Journal 2016;24