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Polymyositis anti-SRP antibodies and pregnancy about 2 cases

Cissé Ousmane
Ba El Hadji Makhtar
Ba Fatoumata
Gams Daniel Massi
Daddah Sami Mouhamed Lémine
Diop-Sène Marieme Soda
Sow Adjaratou Dieynaba
Basse Anna
Seck Lala Bouna
Ndiaye Moustapha
Diop Amadou Gallo
Ndiaye Mouhamadou Mansour


Anti-SRP myopathy represents 4 to 6% of all the inflammatory myopathies. It has been described since the 80s and its influence on pregnancy and vice versa has been highlighted recently. We report two cases of anti-SRP myopathy associated with pregnancy. In the first case, the initial manifestations of the disease started in post partum and the second case was an anti-SRP myopathy patient before pregnancy. In both cases we objectified outbreaks during post-partum. Pregnancy seems to promote outbreaks. The inactive myopathy seems to presents no serious maternal-fetal complications as well as the usual dose of corticosteroids. The treatment (corticosteroid) during pregnancy is indicated given the risk of worsening during the post-partum.

The Pan African Medical Journal 2016;24

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eISSN: 1937-8688