Intravenous thrombolysis with rt-PA in stroke: experience of the moroccan stroke unit

  • Naima Chtaou
  • Lamyae Rachdi
  • Aouatef El Midaoui
  • Zouhair Souirti
  • Nils Wahlgren
  • Mohammed Faouzi Belahsen

Abstract

The majority of strokes are due to blockage of an artery in the brain by a blood clot. Prompt treatment with thrombolytic drugs can restore blood flow before major brain damage has occurred. We report the case series of all patients who were treated with rt-PA at Stroke Unit of HASSAN II University hospital between 2010 and 2013. There were 52 patients treated with intravenous rtPA during the study period. The mean age was 63 years with the no gender predominance (sex ratio 1.02). Hypertension was the most common vascular risk factor (31%) and 17% of patients suffered from atrial fibrillation. 17 of 52 patients (32.7%) were treated within a 3 hours window of stroke onset and 35 of 52 (67.3%) patients were treated within 3-4.5 h. Twenty five patients (48%) had significant early improvements within 24 hours and twenty one (40.3%) patients had good outcomes at 3 months and fifteen patients (29%) died within the same period.

The Pan African Medical Journal 2016;24

Author Biographies

Naima Chtaou
Neurology Department, Hassan II University Hospital, Fez, Morocco
Lamyae Rachdi
Neurology Department, Hassan II University Hospital, Fez, Morocco
Aouatef El Midaoui
Neurology Department, Hassan II University Hospital, Fez, Morocco; Laboratory of Epidemiology and Public Health, Faculty of Medicine and Pharmacy,Sidi Mohammed BenAbdellah university Fez, Morocco
Zouhair Souirti
Neurology Department, Hassan II University Hospital, Fez, Morocco
Nils Wahlgren
Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
Mohammed Faouzi Belahsen
Neurology Department, Hassan II University Hospital, Fez, Morocco; Laboratory of Epidemiology and Public Health, Faculty of Medicine and Pharmacy,Sidi Mohammed BenAbdellah university Fez, Morocco
Published
2016-09-19
Section
Articles

Journal Identifiers


eISSN: 1937-8688