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Familial adenomatous polyposis syndrome with colorectal cancer in two Nigerians: a report of two cases and review of literature


Matthew Olumuyiwa Bojuwoye
Abdulfatai Bamidele Olokoba
Olumuyiwa Ayotunde Ogunlaja
Sulaiman Olayide Agodirin
Olatunde Kazeem Ibrahim
Kenechukwu Chukwuemeka Okonkwo
Aminu Mansa Aliyu

Abstract

Familial adenomatous polyposis syndrome is a rare condition characterized by the presence of numerous adenomatous polyps in the gastrointestinal tract and associated with risk for colorectal cancer. The disease is scarcely reported in Nigeria and this is the index report in Ilorin. Two cases were clinically diagnosed in our facility. They both presented with gastrointestinal bleeding and numerous rectal and colonic polyps were identified at colonoscopy. Histological examination of the polyps in the both cases revealed features in keeping with adenomatous polyps. This report highlights the occurrence of this precancerous condition.


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eISSN: 1937-8688