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Inflammatory myofibroblastic tumor of hard palate: a lesion of extreme rarity


Naman Kirit Pandya
Utsav Umang Bhatt

Abstract

A 19-year young female patient presented with the chief complaint of palatal perforation since 15 days. No significant medical or familial history. No h/o of trauma. On clinical examination (A) a single round perforation was present on hard palate extending antero-posteriorly from distal surface of upper left 1st premolar to mesial surface of upper left 2nd premolar and medio-laterally extending 1 mm medially from marginal mucosa of 1st premolar to 1 cm laterally from mid palatine raphe. Clinically the extension was approx 5×5 mm with normal surrounding mucosa. No tooth mobility was noted. No signs of fluid discharge or nasal regurgitation was found. On palpation all inspectory findings were confirmed. No tenderness on palpation was present. Depth of the lesion was through and through from palatal to buccal cortex. On further radiological examination CBCT (B) showed a single round shape hypodense area between left maxillary premolars, approximately 1×1 cm in diameter. Aggressive destruction of buccal and lingual cortical plate with perforation in floor of maxillary sinus in left premolar region was noted (C and D). External root resorption was seen with both left premolars associated with the lesion. Differential diagnosis considering aggressive maxillary lesion was made as lateral periodontal cyst, traumatic injury and malignant tumor. Patient was planned for excisional biopsy with extraction of involved premolars under local anaesthesia. Histopathological examination revealed plump spindal cells arranged in fascicles and myofibroblastic cells with occasional mitosis. Immuno Histochemistry (IHC) further confirms the morphological findings, which were in consistent with the findings of IMT. Thus IMT of oral cavity should be included as a differential diagnosis of any aggressive lesions or for any localised palatal perforations.


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eISSN: 1937-8688