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Pan African Medical Journal

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Churg-Strauss syndrome associated with AA amyloidosis: a case report

Mouna Maamar, Zoubida Tazi-Mezalek, Hicham Harmouche, Zitouna El Hamany, Mohammed Adnaoui, Mohammed Aouni

Abstract


Churg Strauss syndrome is a rare systemic and pulmonary vasculitis exceptionally associated with AA amyloidosis. We report the case of a 65-year old woman with past medical history of asthma. She developed polyarthralgia, headache and purpura. A laboratory workout found hypereosinophilia (1150/μL), positive p-ANCA, microscopic haematuria and proteinuria at 2g/day. A diagnosis of Churg-Strauss syndrome was established based on five criteria of the American College of Rheumatology (ACR). Renal biopsy showed an important type AA amyloid deposit. The patient was treated with steroids with a good response of the vasculitis and amyloidosis with disappearance of the proteinuria.

Pan African Medical Journal 2012; 12:30



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