Extramedullary plasmocytoma relapsing at differents sites: an unusual presentation

  • Maryame Ahnach
  • Sofia Marouan
  • Mohamed Rachid
  • Abdellah Madani
  • Asmaa Quessar
  • Said Benchekroun
  • Meryem Quachouh

Abstract

Extramedullary plasmacytoma (EMP) is an uncommon plasma cell neoplasm results from plasma cell proliferation and consists of monoclonal plasmacytic infiltration, without bone marrow involvement and any other systemic characteristics of multiple myeloma. EMP accounts for 3% of all plasma cell neoplasms and approximately 80% to 90% of EMP involve submucosa of the upper aerodigestive, while scrotal, dermis and retroperitoneal infiltration are very rare. There are no consensus guidelines for treatment, but EMP is highly radiosensitive, surgery may be considered for some sites, but 11 at 30% can progress in multiple myeloma. We report here an exceptional case of recurrent EMP in much localization. It's about a man 72 years old with initially testicular plasmocytoma who generalized the plasmacytic infiltration after 16 months in skin and progressively in mediastinal and retroperitoneal plasmacytoma, without any medullar and bone involvement.

Pan African Medical Journal 2013; 14:34

Author Biographies

Maryame Ahnach
Department of Hematology and pediatric oncology, 20 August Hospital, Casablanca, Morocco
Sofia Marouan
Department of Pathology, Ibn Rochd Hospital, Casablanca, Morocco
Mohamed Rachid
Department of Hematology and pediatric oncology, 20 August Hospital, Casablanca, Morocco
Abdellah Madani
Department of Hematology and pediatric oncology, 20 August Hospital, Casablanca, Morocco
Asmaa Quessar
Department of Hematology and pediatric oncology, 20 August Hospital, Casablanca, Morocco
Said Benchekroun
Department of Hematology and pediatric oncology, 20 August Hospital, Casablanca, Morocco
Meryem Quachouh
Department of Hematology and pediatric oncology, 20 August Hospital, Casablanca, Morocco
Published
2013-05-01
Section
Articles

Journal Identifiers


eISSN: 1937-8688