Unusual case of cavitary lung metastasis from squamous cell carcinoma of the uterine cervix

  • Soundouss Raissouni
  • Rais Ghizlane
  • Houda Mouzount
  • Kharmoum Saoussane
  • Setti Khadija
  • Fouad Zouaidia
  • Rachida Latib
  • Hind Mrabti
  • Hassan Errihani

Abstract

Spontaneous excavation of primary lung cancer is common; however cavitation of metastatic lung lesions is rare and usually confused with benign lesions. In Moroccan context tuberculosis is the first suspected diagnosis of lung excavations. We report a rare case of cavitary lung metastasis of a uterine cervix cancer, treated initially as tuberculosis. A 40-year old non-smoking woman with a known history of squamous cell carcinoma of the uterine cervix since August 2005; presented on September 2008 with right chest pain without fever, hemoptysis or weight loss. CT scan showed a thin walled cavity. Empirical Antibiotic therapy was conducted 15 days with poor outcome. Then antibacillary treatment was started with no proof of mycobacterial infection. A month later, the patient presented with gynecological bleeding and a pneumothorax. Bronchoscopy with transbronchial biopsy of the cavitary mass was performed. Pathology demonstrated a metastatic squamous cell carcinoma. Pelvic examination and MRI showed a subsequent local cervix recurrence. Patient underwent 3 courses of systemic chemotherapy. She died on June 2009 due to progressive disease. Even cavitary lung metastases are rare and benign differential diagnosis are more common, clinician should be careful in neoplastic context and investigation should be done to eliminate a recurrence.

Pan African Medical Journal 2013; 14:37

Author Biographies

Soundouss Raissouni
Department of medical oncology, National Institute of Oncology, Rabat, Morocco
Rais Ghizlane
Department of medical oncology, National Institute of Oncology, Rabat, Morocco
Houda Mouzount
Department of medical oncology, National Institute of Oncology, Rabat, Morocco
Kharmoum Saoussane
Department of medical oncology, National Institute of Oncology, Rabat, Morocco
Setti Khadija
Department of pathology, Centre Hospitalier IBN SINA, Rabat, Morocco
Fouad Zouaidia
Department of pathology, Centre Hospitalier IBN SINA, Rabat, Morocco
Rachida Latib
Department of Radiology, National Institute of Oncology, Rabat, Morocco
Hind Mrabti
Department of medical oncology, National Institute of Oncology, Rabat, Morocco
Hassan Errihani
Department of medical oncology, National Institute of Oncology, Rabat, Morocco
Published
2013-05-01
Section
Articles

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eISSN: 1937-8688