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Update on lessons learned from glycemia control studies


A Cunningham
A.O. Dokun

Abstract

Diabetes is a major health disorder affecting millions of people worldwide. Numerous studies have confirmed that micro and macrovascular complications ensue as a result of hyperglycemia. Initial studies show that while intensive glycemic control has been shown to reduce microvascular complications in both type 1 and 2 diabetics, macrovascular benefits have only been clearly seen in type 1 diabetics. Conflicting results have emerged regarding the benefits and potential adverse effects of tight glycemic control. Recent studies have emerged demonstrating some macrovascular benefits in type 2 diabetics, though this was associated with increased risk of hypoglycemia in some individuals. Thus, glycemic control in individuals with diabetes may need to be individualized in order to maximize benefits while minimizing adverse effects.

Keywords: Glycemic control, Hyperglycemia, Type 2 diabetes, Glucose


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eISSN: 2467-8252
print ISSN: 2360-7793