Synthesis and antimicrobial activity of azine and 3, 4, 5 – trimethoxy substituted azine

Abstract

Azine and the substituted 3, 4, 5 – trimethoxy azine were synthesized by the condensation of the corresponding Benzaldehyde and substituted Acetophenone with hydrazine hydrate. The compounds synthesized were characterized and screened for anti-microbial activity against Bacillus species, Escherichia coli, Klebsiella pneumonia, serratia marcensces and candida albicans.

Keywords: Azine, antimicrobial activity, 3, 4, 5 – trimethoxy substituted azine