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Scientia Africana

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Synthesis and antimicrobial activity of azine and 3, 4, 5 – trimethoxy substituted azine

P.O. Osarumwense

Abstract


Azine and the substituted 3, 4, 5 – trimethoxy azine were synthesized by the condensation of the corresponding Benzaldehyde and substituted Acetophenone with hydrazine hydrate. The compounds synthesized were characterized and screened for anti-microbial activity against Bacillus species, Escherichia coli, Klebsiella pneumonia, serratia marcensces and candida albicans.

Keywords: Azine, antimicrobial activity, 3, 4, 5 – trimethoxy substituted azine




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