Evidence for zolpidem efficacy in brain damage
AbstractPrevious reports have shown that zolpidem could reverse semi-coma and improve cerebral perfusion after brain injury. Studies in animals have implicated omega 1 GABAergic action as reason for this improvement. Evidence for the efficacy of zolpidem in a wide range of brain pathology is reviewed here and the mechanism of zolpidem in brain injury is considered from the perspective of diaschisis and neurological dormancy after brain injury.
Keywords: Zolpidem, brain injury, dormancy, diaschisis
South African Family Practice Vol. 47(3) 2005: 49-50