PROMOTING ACCESS TO AFRICAN RESEARCH

South African Family Practice

Log in or Register to get access to full text downloads.

Remember me or Register



Gastro-oesophageal reflux: an overview of the pharmacotherapeutic treatment options

L Malan, Q Labuschagne, N Schellack, G Schellack, J.C. Meyer

Abstract


Gastro-oesophageal reflux disease (GORD) produces symptoms that cause great irritation to the patient. Pharmacotherapeutic management is directed at minimising these symptoms and reducing the causative factors, e.g. acid production, thereby providing relief. Currently available agents include simple antacids and acid suppression therapy, including histamine 2-receptor antagonists, proton pump inhibitors, mucosal or cytoprotective agents and pro-motility agents. Deciding on appropriate therapy will depend on the diagnosis, side-effects and cost-effectiveness of the treatment.

Keywords: GORD, gastro-oesophageal reflux, PPIs, proton-pump inhibitors




AJOL African Journals Online