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One-pot, Facile Synthesis of Quinoxaline Derivatives from Bis-aryl &#945;-Hydroxyketones and o-Arenediamines using KMnO<sub>4</sub>/CuSO<sub>4</sub>


A Khorramabadi-zad
M Azadmanesh
S Mohammadi

Abstract

KMnO4/CuSO4, a readily available reagent combination, was found to be effective for the high-yield synthesis of quinoxaline derivatives from bis-aryl -hydroxyketones and o-arenediamines in hot ethanol.

KEYWORDS Quinoxalines, bis-aryl -hydroxyketone, oxidation, Lewis acids, KMnO4, CuSO4.

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eISSN: 1996-840X
print ISSN: 0379-4350