Silica-Supported Yttrium Nitrate Hexahydrate as a Heterogeneous Catalyst for the Synthesis of 2-Amino-4H-Chromenes in Water
Abstract
Silica-supported yttrium nitrate hexahydrate (Y(NO3)3.6H2O/SiO2) has been found to be an efficient and reusable catalyst for the synthesis of 2-amino-4H-chromenes via a one-pot aqueous three-component reaction between arylaldehydes, malononitrile and â-naphthol in high yields. This method has many appealing attributes such as excellent yields, short reactions time, reusability of the catalyst and simple work-up procedure.
KEYWORDS: Silica-supported yttrium nitrate hexahydrate, 2-amino-4H-chromene, malononitrile, arylaldehyde, β-naphthol.
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