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A Simple Three-component Synthesis of 3-Amino-5-arylpyridazine-4-carbonitriles


J Khalafy
M Rimaz
S Farajzadeh
M Ezzati

Abstract

New 3-amino-5-arylpyridazine-4-carbonitriles have been synthesized by a one-pot three-component reaction of malononitrile with arylglyoxals in the presence of hydrazine hydrate at room temperature in water and ethanol.

KEYWORDS Arylglyoxals, arylpyridazines, hydrazine hydrate, one-pot, malononitrile.


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eISSN: 1996-840X
print ISSN: 0379-4350