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South African Journal of Chemistry

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One-pot Synthesis of Substituted Pyrroles with N,N,N’,N’-Tetrachlorobenzene-1,3-disulphonamide and N,N’-Diiodo-N,N’-1,2-ethanediylbis(p-toluenesulphonamide) as Novel Catalytic Reagents

R Ghorbani-Vaghei, H Veisi

Abstract


In this research, N,N,N’N’-tetrachlorobenzene-1,3-disulphonamide as novel catalytic reagent and N,N’-diiodo-N,N’-1,2-ethanediylbis(p-toluenesulphonamide) as new catalyst were used for the synthesis of N-substituted pyrroles in good to excellent yields under mild conditions. These reusable reagents were compared with existing reagents and it is clear that this study is a welcome addition in the field of pyrrole synthesis.

Keywords: Pyrroles, Paal-Knorr reaction, TCBDA, NIBTS, catalytic reagent




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