The Evaluation of Novel Camphor-derived Ligands as Catalysts in the Asymmetric Henry Reaction

  • GA Boyle
  • T Govender
  • HG Kruger
  • GEM Maguire
Keywords: Camphor, asymmetric catalysis, Henry reaction, chiral ligands

Abstract

The evaluation of a series of camphor-derived ligands as catalysts in the asymmetric Henry reaction is reported. The synthesis of two novel derivatives is detailed and these molecules are also screened as catalysts in this reaction. The single crystal X-ray structure of one of the novel compounds is reported. The reaction is catalyzed with moderate to excellent yields and moderate enantioselectivity.

Keywords: Camphor, asymmetric catalysis, Henry reaction, chiral ligands

Published
2015-10-08
Section
Articles

Journal Identifiers


eISSN: 0379-4350