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South African Journal of Chemistry

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Cyclohexenones Through Addition of Ethyl Acetoacetate to 3-Aryl-1-(thiophen-3-yl)prop-2-en-1-one Derivatives

Y Budak, E Findik, M Ceylan

Abstract


Chalcone derivatives 3a–i containing a thiophene ring were prepared by the condensation of 1-(thiophen-3-yl)ethanone with aromatic aldehydes in excellent yields. The Michael addition of ethyl acetoacetate 4 to chalcone derivatives 3a–i resulted in the formation of nine novel ethyl 6-aryl 4-(3-thienyl)cyclohex-3-en-2-one-1-carboxylate derivatives 6a–i.

Keywords: Michael Addition, Ethyl Acetoacetate, Cyclohexenones, Cyclocondensation




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