Synthesis of 9H-Indeno [1, 2-b] Pyrazine and 11H-Indeno [1, 2-b] Quinoxaline Derivatives in One-step Reaction from 2-Bromo-4-chloro-1-indanone

  • S Jasouri
  • J Khalafy
  • M Badali
  • RH Prager
Keywords: 2-bromo-4-chloro-1-indanone, diaminopyridine, indeno[1, 2-b]quinoxaline, 2-b]pyrazine, debromination

Abstract

The reaction of 2-bromo-4-chloro-1-indanone with 2,3-diaminomaleonitrile, benzene-1,2-diamine and 4-methylbenzene-1,2-diamine in glacial acetic acid gave 8-chloro-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile, 1-chloro-11H-indeno[1,2-b]quinoxaline and 1-chloro-7-methyl-11H-indeno[1,2-b]quinoxaline, respectively, in good yield.

Keywords: 2-bromo-4-chloro-1-indanone, diaminopyridine, indeno[1,2-b]quinoxaline, indeno[1,2-b]pyrazine, debromination

Published
2015-10-12
Section
Articles

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eISSN: 0379-4350