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Kaposi's sarcoma, non-Hodgkin's lymphoma (NHL), including primary central nervous system lymphoma (PCNSL), and cervical cancer define the acquired immune deficiency syndrome (AIDS). NHL is the second most common malignancy associated with HIV
infection. The clinical presentation varies, and while patients may present with symptomatic lymphadenopathy, many have extranodal disease. Extranodal lymphomas arise from tissue other than lymph nodes and even sites that normally contain no lymphoid tissue. These lymphomas are referred to as extranodal lymphomas and can arise in almost any organ. AIDS-NHL may present at any point in the course of immunosuppression. This report deals with three case studies that illustrate the spectrum and variety of extranodal presentations in patients with AIDS-NHL.
Southern African Journal of HIV Medicine Vol. 6 (1) 2005: pp. 37-40