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Acebutolol in Cardiac Arrhythmias


BS Lewis
AS Mitha
MS Gotsman

Abstract

Acebutolol (Sectral), a new beta-adrenoceptor antagonist, was used in 44 patients with cardiac arrhythmias (53 episodes). It was used intravenously (12,5 and 25 mg), orally (100 mg every 8 hours) or in combination with quinidine. Acebutolol was most effective in supraventricular tachyarrhythmias, to control the ventricular response when digital's was ineffective, as a synergist with quinidine to convert patients to sinus rhythm, or prophylactically to prevent relapse to atrial fibrillation. It also terminated ventricular tachycardia in two patients. Side-effects occurred in three ill patients.

S. Afr. Med. J., 48, 821 (1974).

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eISSN: 2078-5135
print ISSN: 0256-9574