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A Simple Automated System for the Routine Production of <sup>99m</sup>Tc by Methyl-Ethyl-Ketone Extraction


JF Klopper
PDR van Heerden
UD Muller
WP Baard

Abstract

A relatively simple, automated system for the rapid, efficient and safe routine production of 99mTc04 from 99Mo03 by the methyl-ethyl-ketone (MEK) extraction technique is described. The 4 phases of the extraction process - bubbling of air, phase separation, drawing off of 99mTc in MEK, and evaporation to dryness, are controlled by an automatic timer, suction-pressure pump and solenoid switches. The eluate was found to contain neither bacterial organisms or pyrogens nor significant levels of alumina and radio-isotopic impurities. With this system it is possible to make use of locally produced "Mo, even of low specific activity for the routine production of "'"'lc in any concentration required.

S. Afr. Med. J., 48, 998 (1974).

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eISSN: 2078-5135
print ISSN: 0256-9574