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Detection of Australia antigen (HBAg) in blood donors and hepatoma patients in Mozambique


L.L. Reys
O.A. Sequeira

Abstract

The evaluation of three different methods (counter mmuno-electrophoresis, latex agglutination and radioimmunoassay) for Australia antigen detection is discussed with regard to their sensitivity in the analysis of sera from blood donors and primary liver cancer patients. The counter immuno-electrophoretic method is the least sensitive, particularly in the analysis of sera from hepatoma patients. The latex agglutination test seems to have the same reliability in both groups, but gave a higher percentage of positive results compared with the radioimmunoassay technique. The value of an improved latex agglutination test for Australia antigen detection in field work in southern Mozambique, is stressed.

S. Afr. Med. J. 48, 267 (1974).

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eISSN: 2078-5135
print ISSN: 0256-9574