PROMOTING ACCESS TO AFRICAN RESEARCH

South African Medical Journal

The AJOL site is currently undergoing a major upgrade, and there will temporarily be some restrictions to the available functionality.
-- Users will not be able to register or log in during this period.
-- Full text (PDF) downloads of Open Access journal articles will be available as always.
-- Full text (PDF) downloads of subscription based journal articles will NOT be available
We apologise for any inconvenience caused. Please check back soon, as we will revert to usual policy as soon as possible.





Aetiology and antenatal diagnosis of spina bifida

K Fieggen, C Stewart

Abstract


Spinal neural tube defects (NTDs) result from failure of neural tube closure that normally occurs at 15 - 28 days after conception. Birth prevalence figures for spina bifida vary, but on average are around 0.1%. There are no recent figures for South Africa, but previous studies have shown an incidence of 0.77 - 6.1/1 000 live births, with higher incidences in rural areas. The true incidence of NTDs is thought to be higher, but is difficult to calculate as this includes both spontaneous and therapeutic pregnancy losses.



http://dx.doi.org/10.7196/SAMJ.8039
AJOL African Journals Online