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Wound healing with honey - a randomised controlled trial


Ronald Ingle
Jonathan Levin
Krijn Polinder

Abstract

Objectives. To compare honey and IntraSite Gel as woundhealing agents, to record side-effects, gauge patient satisfaction and calculate the  cost-effectiveness of the honey used.

Design and setting. A prospective, randomised, double-blind controlled trial was carried out among goldmine workers.

Outcome measures. Outcome measures were healing times of shallow  wounds and abrasions; side-effects; patient satisfaction with treatment; and amount of honey and IntraSite Gel used.

Results
. The mean healing times of shallow wounds treated with honey or  with IntraSite Gel did not differ significantly (p = 0.75, 95% confidence  interval (CI): -5.41; 7.49 days). When adjusted for wound size, the 2.8-day difference in favour of honey was not significant (p == 0.21, 95% CI: -2.41; 8.09). In the case of abrasions there was also no significant  difference (p = 0.83, 95% CI: -4.98; 6.19 days). When adjusted for wound
size, the difference of 0.22 days in favour of IntraSite Gel was not    significant (p = 0.94, 95% CI: -5.72; 6.15.4). Of patients treated with honey, 27% and 10% respectively experienced itching and pain, and 2  experienced burning for a short time after application. Of patients treated with IntraSite Gel, 31% experienced itching. All patients in both treatment groups were either satisfied or extremely satisfied with treatment. The average cost of treatment per patient was R0.49 with honey and R12.03 with with IntraSite Gel.

Conclusions. A distinction should be made between shallow wounds and  abrasions when wound healing is being measured. There was no evidence of a real difference between honey and IntraSite Gel as healing agents. Honey is a safe, satisfying and effective healing agent. Natural honey is extremely costeffective.


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eISSN: 2078-5135
print ISSN: 0256-9574