'n Vergelyking van drie verskillende tegnieke die berekening van glomerulere filtrasiespoed

  • C.P. Herbst
  • M. Dunn
  • A.C. Viviers
  • M. Van Zyl
  • A Van Aswegen
  • A.C. Otto


The clearance of inulin, creatinine and radioactive tracers from the blood may be used to measure glomerular filtration rate (GFR). These techniques, however, are usually invasive and time-consuming. Although the clearance of a radioactive tracer is usually applied in nuclear medicine for the determination of GFR, it is also possible to convert the concentration of the tracer in the kidneys to absolute GFR by means of a regression equation. As this new technique is much faster, we have compared it with the conventional technique. A good correlation was found with the standard radionuclide techniques (r = 0,91), but the reference method was underestimated on the average by 14 ml/min. The new regression equation derived in our clinic will ensure future accurate GFR measurements within 6 minutes.


Journal Identifiers

eISSN: 0256-95749
print ISSN: 2078-5135