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South African Medical Journal

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Human Chorionic Gonadotrophin in the Treatment of Threatened and Recurrent Abortion

WH Utian

Abstract


Early experience with the use of human chorionic gonadotrophin replacement therapy in a small number of progesterone-deficient pregnancies is presented. Twelve out of 15 pregnancies proceeded normally to term and 3 pregnancies were lost. The latter group was associated with blighted ova and a significant amount of trophoblastic tissue. The findings in this small preliminary trial appear to justify a broader controlled investigation into the value of HCG therapy in prevention of threatened or recurrent abortion associated with progesterone insufficiency.

S. Afr. Med. J., 48, 769 (1974).



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