Acebutolol in Cardiac Arrhythmias

  • BS Lewis
  • AS Mitha
  • MS Gotsman

Abstract

Acebutolol (Sectral), a new beta-adrenoceptor antagonist, was used in 44 patients with cardiac arrhythmias (53 episodes). It was used intravenously (12,5 and 25 mg), orally (100 mg every 8 hours) or in combination with quinidine. Acebutolol was most effective in supraventricular tachyarrhythmias, to control the ventricular response when digital's was ineffective, as a synergist with quinidine to convert patients to sinus rhythm, or prophylactically to prevent relapse to atrial fibrillation. It also terminated ventricular tachycardia in two patients. Side-effects occurred in three ill patients.

S. Afr. Med. J., 48, 821 (1974).

Author Biographies

BS Lewis
Cardiac Unit, Wentworth Hospital and University of Natal, Durban
AS Mitha
Cardiac Unit, Wentworth Hospital and University of Natal, Durban
MS Gotsman
Cardiac Unit, Wentworth Hospital and University of Natal, Durban
Published
2018-02-18
Section
Articles

Journal Identifiers


eISSN: 0256-95749
print ISSN: 2078-5135