Generation of small bowel mucosa
Following massive bowel resection, the characteristic features of a 'short bowel' syndrome develop. Some patients respond to medical treatment but may succumb later to the effects of deficient absorption. Some surgical procedures devised for delaying transit through the bowel, are mentioned.
The patient lacks absorptive surface of the bowel. Experiments performed on mongrel dogs to produce generation of mucosa and the results obtained, are described. Further experiments were carried out to show that this generated mucosa has absorptive capacity.