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Jun 22, 2018Article Details
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Main Article Content
The association of pituitary hypofunction with chronic diarrhoea: a report of two cases
Abstract
Panhypopituitarism is a rare disease and the majority of cases which do occur are either secondary to postpartum haemorrhage or to surgical removal of the gland. It is, however, well-known that features of the condition may occur in persons who are grossly malnourished. A striking point in such cases has been the reversion to normal once the general nutrition has been improved and for this reason such subjects have been labelled as examples of 'functional hypopituitarism'.
The present paper describes two cases of panhypopituitarism in whom chronic diarrhoea with malnutrition antedated the onset of the endocrine disorder. In both ubjects the pituitary failure seemed to be severe and irreversible. Because of the variety of such an association, it seems worth while reporting these two cases in detail.
