South African Medical Journal

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Human chorionic gonadotrophin in the treatment of threatened and recurrent abortion

W.H. Utian


Early experience with the use of human chorionic gonadotrophin replacement therapy in a small number of progesterone-deficient pregnancies is presented. Twelve out of 15 pregnancies proceeded normally to term and 3 pregnancies were lost. The latter group was associated with blighted ova and a significant amount of trophoblastic tissue. The findings in this small preliminary trial appear to justify a broader controlled investigation into the value of HCG therapy in prevention of threatened or recurrent abortion associated with progesterone insufficiency.

S. Afr. Med. J., 48, 769 (1974).

AJOL African Journals Online