South African Medical Journal

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Guideline for the diagnosis and management of multiple sclerosis: A Southern African perspective

DL Giampaolo, A Bhigjee, C Retief, M Isaacs, M Britz, D Opperman, R Govender, M van Rensburg


Before making a diagnosis of multiple sclerosis (MS), it is imperative that alternative diagnoses are considered and excluded. This is particularly  important in South Africa, which is a moderate prevalence MS area, has a high burden of neurological infections and where the majority of the people are  black – an ethnic group that has a very low frequency of MS. Before applying diagnostic criteria, there should be no better explanation for the patient’s presentation. This guideline, written on behalf of the Multiple Sclerosis Society of South Africa, aims to assist in the diagnosis and treatment of MS in Southern Africa.
AJOL African Journals Online