Botulinum Toxin – Treatment Of Choice For Primary Hyperhidrosis?

Abstract

The term Botulinum toxin encompasses a group of seven (A – G) immunologically distinct Zinc-dependent endoproteases that act primarily at peripheral cholinergic synapses. By blocking synaptic vesicle trafficking they effectively block the release of Acetylcholine inducing muscle paralysis. This property is utilized in the treatment of conditions such as blepharospasm, torticollis and focal dystonias

Sud. j. dermatol Vol.2(1) 2004: 16-19