Mancozeb has inhibited the reproduction mechanism in male domestic pigeons (Columba livia domestica) and altered hepatic function

Abstract

Pesticides are toxic chemicals, very much used in agriculture in order to increase the agricultural outputs. These molecules can affect reproductive function of animals. This study aimed to the toxicity of the fungicide mancozèb on certain blood biochemical markers and seasonal reproduction of male domestic pigeons (Columba livia domestica) under long photoperiod (20L: 04D). The fungicide was orally administered at 2 and 5 g/l (doses used in agriculture). The obtained results revealed that under a long photoperiod, the sexual activity lasted only 04 weeks. In addition, mancozeb administration induced gonadic regression, delayed the refractory phase, provoked a hyperglycemia, a hyperlipidemia, an elevation in the activity of alkaline phosphatase and aminotransferase, and a reduction in creatinine level. The toxic effects of mancozeb was apparent in higher doses. To conclude, mancozeb has inhibited the reproduction mechanism in male pigeons and altered hepatic function.