Tropical Journal of Health Sciences

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Experience with Surgical Management of Gastro-duodenal Peroration at a Federal Medical Centre in North-Central Nigeria

A.A. Adejumo, O.J. Ajamu, O.O. Akanbi, J.C. Onwukwe, O.A. Adeosun, O.P. Omoregie


Many patients with peptic ulcer disease (PUD)  present to the surgeon with complications of the disease. Many of these patients may eventually require immediate surgical intervention which may be operative. This study looked at the pattern of presentation, predisposing factors, appraise management protocols. This was a retrospective study of 71 patients out of a total of 104 who were managed for complications of peptic ulcer disease.  Data were analyzed using Epi info statistical package.

Seventy-one patients were seen with gastroduodenal perforations. Out of these, 62 (87.3%) were males and 9 (12.7%) were females (M:F= 6.9:1).  Primary closure with modified Graham’s patch was done in over 70% of the patients. Complications encountered include surgical site infection (13, 18%), superficial wound dehiscence (11, 15%), residual peritoneal abscess (3,4%), burst abdomen (4, 6%) and septic shock (2,3%).

Complications of PUD as exemplified by gastroduodenal perforations were the commonest complications observed in our study. These were largely managed operatively with satisfactory outcome.

Keywords: Peptic ulcer, Gastroduodenal perforations, Keffi

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