Serum Chilamydia trachomatis –IgG antibody in Nigerians attending infertility clinic

  • CC Onyenekwe Chemical Pathology Department College of Health Sciences, Nnamdi Azikiwe, University, Nnewi Campus, PMB 5001, Nnewi, Anambra State, Nigeria
  • SC Meludu Chemical Pathology Department College of Health Sciences, Nnamdi Azikiwe, University, Nnewi Campus, PMB 5001, Nnewi, Anambra State, Nigeria
  • CE Dioka Chemical Pathology Department College of Health Sciences, Nnamdi Azikiwe, University, Nnewi Campus, PMB 5001, Nnewi, Anambra State, Nigeria
Keywords: Chlamydia trachomatis, IgG antibody, men, women, Nigeria

Abstract

Objective and Design: The present study was designed to detect serum concentration of Chlamydia trachomatis –IgG antibody in Nigerian men and women as non –invasive test for the detection of C. trachomatis infection in Lagos,Nigeria.

Subjects, Outcome Measures: Two hundred and twenty seven (184 women and 43 men) subjects aged 25 -40years were recruited for the study at a fertility clinic. Venous blood samples were drawn from the subjects and serological detection of C. trachomatis –IgG antibody was assyed by solid phase immunoassay technique.

Results: The results showed that 75 (41%) and 22(51%) of the women and men respectively had positive C. Trachomatis – IgG titres. However, the prevalence in women and men were similar (X2 = 1.15, P =02).

The subjects positive for C. Trachomatis infection had different C. trachomatis antibody titers. This might be a reflection of the severity of the infection in the positive individuals. The severity of the infection is not sex associated ( X2 = 1.91, p =0.38).

Conclusions: In conclusion, there is high incidence of C. trachomatis infection amongst Nigerian men and women. This may portend grave consequences if undetected early as it could lead to damage of the reproductive tract.

Key Words: Chlamydia trachomatis, IgG antibody , men women, Nigeria.

Tropical Journal of Medical Research Vol.8(1) 2004: 1-4
Published
2004-07-22
Section
Articles

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eISSN: 1119-0388