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Management of HIV in pregnancy: a clinical review


Chris O Agboghoroma

Abstract

Context: The prevalence rate of HIV infection in pregnant women in some African countries is over 30 percent. HIV may adversely affect pregnancy outcome leading to spontaneous abortion, premature delivery, intrauterine growth restriction and low birth weight infants. The natural perinatal transmission risk varies from 15-45%. With improved
scientific knowledge in antiretroviral therapy, obstetric care and infant feeding practices, it is now possible to achieve and sustain satisfactory maternal health and prevent perinatal transmission. The application of these strategies has resulted in substantial reduction in perinatal transmission risks (less than 2%) in developed countries.

Objective: This article reviews the specific strategies in the management of HIV positive pregnant woman. It is also meant to serve as guide to health workers who provide care for HIV positive pregnant women.

Methodology: Extensive literature search and review of journal/internet articles, WHO publications, international and local guidelines on management of HIV in pregnancy.

Conclusion: Within the setting of maternity services, HIV positive women can be diagnosed and managed appropriately. The care should be multidisciplinary, sensitive, non-stigmatizing, non-discriminatory and supportive. The capacity to achieve this can be developed through training and retraining of health care workers.

Keywords: human immunodeficiency virus, HIV, pregnancy, perinatal transmission

Tropical Journal of Obstetrics and Gynaecology Vol. 22(1) 2005: 65-73

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eISSN: 0189-5117