Antimicrobial sensitivity pattern of symptomatic urinary tract infection in pregnancy in Aminu Kano Teaching Hospital
Objective: To determine sensitivity pattern of antimicrobial organism in women presenting with features of urinary tract infections in pregnancy in Aminu Kano teaching hospital Kano.
Methods: Retrospective study carried out between January to December 2010, amongst pregnant women attending our antenatal clinic. Those with urinary symptoms had their urine sent for bacteriological examination. Sociodemographic information, results of urine investigations obtained from patients' case records, and analyzed using EPI info statistical software version 6. Significant associations tested using chisquare test and p<0.05 was considered significant.
Results: Seventy-two women had positive results. 7565 women attended antenatal clinic , incidence of UTI 1.3%. Six bacterial isolates identified. Most common was Proteus Mirabilis 24(33.3%), E. Coli 25(25%), staphylococcus Saprophyticus 12(16.6%) Kleibsella aerogenes 10(13.9%), Enterococcus Faecalis 6(8.3%) and Pseudomonas aeriginosa 2 (2.8%), differences were statistically significant (p = 0.015). Sensitivity patterns for
Proteus Mirabilis 12(50%) gentamicin, 7(29.1%) nitrofurantoin, 4(16.7%) augmentin and 1(5.6%) ofloxacine , differences statistically significant (p = 0.0037). Highest number of bacterial isolates obtained in women 20-25
years (40.28 %) statistically significant, p = 0.0005. UTI commoner among women parity 1-2 (54.2%), not statistically significant, p = 0.35.
Conclusion: Commonest organism causing UTI in pregnancy in this study was proteus mirabilis, and is most sensitive to gentamicin.
Summary: Urinary tract infections (UTI) in pregnancy have clinical presentation. A retrospective study of seventytwo pregnant women was carried out in AKTH to determine the antimicrobial sensitivity pattern, in pregnant women presenting with features of UTI. The commonest organism isolated from the urine of these women was proteus mirabilis (33.3%), which was sensitive to gentamicin (50%) compared to augmentin (16.7%)
Keywords: prevalence, aetiology, antimicrobial sensitivity, UTI pregnant women, AKTH
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