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Published:
Apr 30, 2026DOI:
10.4314/tjpr.v25i4.4Keywords:
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Main Article Content
Antimicrobial stewardship and survey of multidrug-resistant bacteria in selected healthcare facilities in Delta State, Nigeria
Abstract
Methods: Relevant institutional review boards gave ethical approval. Questionnaires were delivered to 26 healthcare professionals working in Eku Baptist Government Hospital and 36 professionals in Central Hospital, Warri, to determine their knowledge of antimicrobial stewardship programs (ASPs). Demographics, clinical history, antimicrobial use, laboratory results, and treatment outcomes of 306 cases of Eku Baptist Government Hospital and 200 cases of Warri Central Hospital were assessed through a retrospective review of 506 case notes, laboratory reports and pharmacy records of 2021-2024.
Results: Both hospitals reported limited resources (approximately 72 % inadequate) and low ASP awareness (28-33 %). There was poor training (24-28 %), particularly by nurses in both hospitals. The use of broad-spectrum antimicrobials such as metronidazole and ceftriaxone was frequently prescribed in both hospitals, as a result of empirical prescribing, due to the lack of diagnostic ability. Poor practices in infection control and junior workforce (72.6 % had less than 3 years of experience) worsen AMR issues.
Conclusion: There are severe gaps in antimicrobial stewardship in these hospitals. The AMR risks in resource-limited environments require strengthened ASPs that are achieved by resource allocation, standardized protocols, and continuous training.
