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Tropical Journal of Pharmaceutical Research

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Incidence and Antibiotic Susceptibility Pattern of Bacterial Isolates from Wound Infections in a Tertiary Hospital in Nigeria

A Mohammed, GO Adeshina, YK Ibrahim

Abstract


Purpose: To investigate the incidence of different bacteria isolates in 150 wound infections in Aminu Kano Teaching Hospital, Kano, Nigeria and their antibacterial susceptibility patterns.
Methods: Wound swab samples were collected from general culture bench of the Microbiology Department, after obtaining consent from the hospital’s Medical Advisory Committee, and cultured for bacterial isolates. The isolates were characterized and identified by standard microbiological methods. Antibiotic susceptibility testing was carried out using Kirby-Bauer-CLSI modified Disc Agar Diffusion technique.
Results: Out of the 150 specimens collected, 82 % were infected with bacteria made up predominantl of Staphylococcus aureus (22 %), Pseudomonas aeruginosa (19.9 %), Citrobacter spp (15 %), Escherichia coli (14.7 %) and Proteus mirabilis (14.5 %). In vitro antibiotic susceptibility tests showed that Pseudomonas aeruginosa was susceptible to ceftazidime, ciprofloxacin and gentamicin while the enteric bacteria were generally more resistant to ceftazidime, gentamicin and ciprofloxacin.
Conclusion: The findings show that there is a high rate of wound infection in Kano, Nigeria and that antibiotic-resistant bacteria are present in the wound sites.

Keywords: Wound infection , Antibiotic, Susceptibility, Bacterial resistance




http://dx.doi.org/10.4314/tjpr.v12i4.26
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