Serological Evaluation of the Response of Nigerian Dogs to Flury (Lep) Vaccine

  • A.B. Ogunkoya Department of Veterinary Surgery & Medicine Faculty of Veterinary Medicine, Ahmadu Bello University, Zaria
  • A.J. Hassan Department of Veterinary Surgery & Medicine Faculty of Veterinary Medicine, Ahmadu Bello University, Zaria
  • B.M. Jahun Department of Veterinary Surgery & Medicine Faculty of Veterinary Medicine, Ahmadu Bello University, Zaria
  • A.S. Yilla Department of Veterinary Surgery & Medicine Faculty of Veterinary Medicine, Ahmadu Bello University, Zaria
  • M. O. V. Oshinubi Department of Veterinary Surgery & Medicine Faculty of Veterinary Medicine, Ahmadu Bello University, Zaria
  • G.W. Beran Department of Public Health Prevention Medicine and Microbiology, Veterinary Faculty, Iowa State University, Ames Iowa State U.S.A.

Abstract

Blood samples were taken from a total of 140 dogs that have been vaccinated against rabies at least 15 days earlier and from some that have received anti-rabies vaccine for more than once. A rapid fluorescent focusing inhibition test (RFFIT) was carried out to measure the level of neutralizing antibody (SN) in the blood of these dogs. Result showed that only 54.3% of the dogs have adequate SN titre and therefore could be considered immuned. Dogs, 19 months old and above responded more to immunization than dogs of lower age groups.

Keyword: Rabies, vaccine serum neutralizing antibodies, flury LEP

Trop. Vet. Vol. 21 (2) 15-20 (2003)
Section
Articles

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eISSN: 0794-4845