African Journal of Biotechnology

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Antimicrobial activity of silver nanoparticles synthesized by the fungus Curvularia inaequalis

Helinando P de Oliveira, Leonardo S Cavalcanti, Noelly B. Cavalcanti, Ismara de S Nascimento, Sergio F Pascholati, Luis FP Gusmão, Alan Greison C Macêdo, Mateus Matiuzzi da Costa


Silver nanoparticles have been widely reported in literature due to their vast industrial application in different areas. In this work, we explored a simple procedure for the biosynthesis of silver nanoparticles at room temperature from the action of Curvularia inaequalis as reduction agent. The degree of aggregation and size of biosynthesized particles were optimized from a factorial design involving combined variation of three different parameters of preparation. The resulting colloidal dispersion of silver nanoparticles presented strong antimicrobial activity against Escherichia coli and Klebsiella pneumoniae in an indication that C. inaequalis represents a new potential candidate for alternative biosynthesis of silver nanoparticles with antimicrobial activity.

Keywords: Antimicrobial activity, fungi, silver nanoparticles

African Journal of Biotechnology Vol. 12(20), pp. 2917-2923

AJOL African Journals Online